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Traffic pollution can impair brain function, say B.C. researchers

Groundbreaking UVic and UBC study finds even brief exposures have adverse effects on human brain
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Functional magnetic resonance imaging (fMRI) shows decreased functional connectivity in the human brain after exposure to traffic pollution. (Courtesy UBC Faculty of Medicine)

Common levels of traffic pollution can hinder cognitive function within a matter of only hours, a new study by the University of Victoria and the University of British Columbia has found.

The study, published earlier this month in the journal Environmental Health, provides the first evidence in humans 香蕉视频直播 from a controlled experiment 香蕉视频直播 of altered brain network connectivity directly linked to pollution.

It also found that just two hours of exposure to diesel exhaust causes a decrease in the brain香蕉视频直播檚 functional connectivity, which reflects the ability of different areas of the brain to interact and communicate with one another.

香蕉视频直播淔or many decades, scientists thought the brain may be protected from the harmful effects of air pollution,香蕉视频直播 Dr. Chris Carlsten, professor and head of respiratory medicine and the Canada Research Chair in occupational and environmental lung disease at UBC, said in a news release Tuesday (Jan. 24).

For the experiment, 25 healthy adults were briefly exposed to diesel exhaust and filtered air at different times in a laboratory setting. The brain activity of participants was additionally measured before and after each exposure using functional magnetic resonance imaging (fMRI).

Researchers analyzed changes in the brain香蕉视频直播檚 default mode network (DMN), a set of inter-connected brain regions that play a significant role in memory and internal thought. The fMRIs revealed that participants had decreased functional connectivity in widespread regions of the DMN after exposure to diesel exhaust, compared to filtered air.

香蕉视频直播淲e know that altered functional connectivity in the DMN has been associated with reduced cognitive performance and symptoms of depression, so it香蕉视频直播檚 concerning to see traffic pollution interrupting these same networks,香蕉视频直播 Jodie Gawryluk, assistant professor of psychology at UVic, told Black Press Media. 香蕉视频直播淏ut more studies are needed to look at the long-term effects, like what happens after we have repeated exposures for a long time 香蕉视频直播 we might not be able to recover so easily from that.香蕉视频直播

香蕉视频直播淎ir pollution is now recognized as the largest environmental threat to human health and we are increasingly seeing the impacts across all major organ systems,香蕉视频直播 said Carlsten. 香蕉视频直播淚 expect we would see similar impacts on the brain from exposure to other air pollutants, like forest fire smoke. With the increasing incidence of neurocognitive disorders, it香蕉视频直播檚 an important consideration for public health officials and policymakers.香蕉视频直播

The study was conducted at UBC香蕉视频直播檚 Air Pollution Exposure Laboratory at Vancouver General Hospital, which is equipped with a state-of-the-art exposure booth that is able to mimic what it香蕉视频直播檚 like to breathe a range of different air pollutants.

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